Tosse crônica e síndrome de hipersensibilidade à tosse
Chronic cough and cough hypersensitivity syndrome
Rosana Câmara Agondi
Resumo
A tosse crônica é uma condição prevalente no mundo, em todas as faixas etárias. Trata-se de um distúrbio complexo e de difícil tratamento, pois diversas condições pulmonares e extrapulmonares podem se manifestar com tosse crônica, que, por sua vez, pode ocorrer sem uma causa identificável ou ser resistente a terapias destinadas a tratar as diversas condições associadas à tosse crônica. A maioria dos pacientes com tosse crônica apresenta hipersensibilidade ao reflexo da tosse, ou seja, apresenta tosse em resposta a estímulos relativamente inócuos, o que causa considerável comprometimento de qualidade de vida e impacto psicológico. Nos últimos anos, houve uma mudança de paradigma no diagnóstico de tosse crônica refratária, reconhecendo-a como uma condição distinta, resultado da hipersensibilidade ao reflexo da tosse ao invés de ser apenas um sintoma decorrente de condições subjacentes. Nesta revisão, temos uma atualização sobre tosse crônica, realçando a hipersensibilidade ao reflexo à tosse.
Palavras-chave
Abstract
Chronic cough is a prevalent condition worldwide, affecting individuals across all age groups. It is a complex and difficult-to-treat disorder, as multiple pulmonary and extrapulmonary conditions can present with chronic cough, which in turn may occur without an identifiable cause or be resistant to therapies targeting the various associated conditions. Most patients with chronic cough exhibit cough reflex hypersensitivity - that is, they cough in response to relatively innocuous stimuli -, causing significant impairment in quality of life and psychological burden. In recent years, there has been a paradigm shift in the diagnosis of refractory chronic cough, recognizing it as a distinct condition resulting from cough reflex hypersensitivity rather than merely a symptom of underlying conditions. In this review, we provide an update on chronic cough, highlighting cough reflex hypersensitivity.
Keywords
References
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Submitted date:
01/16/2025
Accepted date:
01/27/2025
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