Síndrome Inflamatória Multissistêmica associada à COVID-19: uma complicação pediátrica da pandemia
COVID-19-associated Multisystem Inflammatory Syndrome: a pediatric complication during the pandemic
Juliano José Jorge; Isabella Bassetti
Resumo
Desde o surgimento da pandemia de COVID-19, casos de febre e inflamação sistêmica tardias, similares à Doença de Kawasaki, têm surgido na população pediátrica, sendo denominados Síndrome Inflamatória Multissistêmica associada à COVID-19. Estes quadros podem ir de apenas febre prolongada, até grave envolvimento gastrointestinal e cardíaco, com choque refratário e falência de múltiplos órgãos. Aneurismas de carótida podem surgir na evolução, levando a complicações em longo prazo. O pronto reconhecimento desta entidade com tratamento precoce de suporte geral, uso de imunoglobulina humana endovenosa e outras drogas imunomoduladoras, pode evitar evolução para casos graves e até mesmo fatais, assim como proteger o paciente de complicações crônicas, principalmente cardíacas.
Palavras-chave
Abstract
Since the emergence of the COVID-19 pandemic, cases of late fever and systemic inflammation similar to Kawasaki Disease have appeared in the pediatric population, this entity was called Multisystem Inflammatory Syndrome associated with COVID-19. The presentation can range from just prolonged fever to severe gastrointestinal and cardiac involvement with refractory shock and multiple organ failure. Carotid aneurysms can arise in the course leading to long-term complications. The prompt recognition of this syndrome with early treatment with general support, use of Human Intravenous Immunoglobulin and other immunomodulatory drugs, can prevent progression to severe and even fatal cases, as well protect the patient from chronic complications, especially the cardiac ones.
Keywords
Referências
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Submetido em:
27/02/2021
Aceito em:
07/09/2021
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