Arquivos de Asma, Alergia e Imunologia
https://aaai-asbai.org.br/article/doi/10.5935/2526-5393.20200052
Arquivos de Asma, Alergia e Imunologia
Original Article

Correlação entre o autodiagnóstico de alergia alimentar e a presença de IgE específica

Correlation between self-diagnosis of food allergy and presence of specific IgE

Fernanda Carolina Pereira Eismann; Vitória Destro Venturim; Bruno Acatauassu Paes Barreto

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Resumo

Introdução: Nos últimos anos a prevalência de alergia alimentar tem aumentado, contudo, o número de autodiagnósticos errados, também. Essa superestimação dos diagnósticos, frequentemente, culmina em dietas restritivas desnecessárias que podem, muitas vezes, ocasionar mais danos do que benefícios para a saúde. Objetivo: Avaliar a relação entre o autodiagnóstico de alergia alimentar e a presença de IgE específica para o referido alimento. Método: Trata-se de um estudo transversal e observacional que avaliou 100 pacientes que aceitaram participar da pesquisa, com idade entre 18 e 75 anos, por meio de um questionário próprio para investigação do autodiagnóstico de doenças alérgicas e um teste cutâneo de leitura imediata ou prick test para detecção de IgE específica para alimentos que podem induzir a uma reação alérgica. Resultados: Foram aplicados e analisados 100 questionários em voluntários na faixa etária de 18 a 75 anos. Destes, 35 pacientes afirmaram ter alergia alimentar durante a aplicação do questionário. Apenas 10 tiveram resultado positivo ao prick test. A maioria dos resultados positivos no prick test estavam associados ao camarão, ao amendoim e ao caranguejo. Conclusão: O presente estudo evidenciou uma importante superestimação do número de autodiagnósticos de alergias alimentares, sendo o número de pacientes que se autodeclararam alérgicos a alimentos consideravelmente maior do que os resultados positivos no prick test. Constata-se que é necessário mais estudos que possuam em sua metodologia informações pré e pós-testes diagnósticos de alergia alimentar, para uma correta avaliação da proporção de casos.

Palavras-chave

Alergia e imunologia, hipersensibilidade alimentar, autoavaliação diagnóstica.

Abstract

Introduction: In recent years, the prevalence of food allergy has increased, as well as the number of incorrect self-diagnoses. This overestimation of diagnoses often culminates in unnecessary restrictive diets that may cause more harm than benefits to health. Objective: To evaluate the relationship between self-diagnosis of food allergy and the presence of specific IgE for that food. Method: This is a cross-sectional and observational study that evaluated 100 patients who agreed to participate in the research, aged between 18 and 75 years. A questionnaire was used to investigate the self-diagnosis of allergic diseases, and a skin prick test was used to detect food-specific IgE that may induce an allergic reaction. Results: One hundred questionnaires were administered and analyzed in volunteers aged from 18 to 75 years. Of these, 35 patients claimed to have food allergy during the administration of the questionnaire. Only 10 tested positive on the prick test. Most positive prick test results were associated with shrimp, peanut, and crab. Conclusion: The present study showed an important overestimation of the number of self-diagnosed food allergies, as the number of patients who self-reported being allergic to food was considerably greater than that of positive prick test results. More studies that have in their methods pre- and post-diagnostic information from food allergy tests are needed for a correct assessment of the proportion of cases.

Keywords

Allergy and immunology, food hypersensitivity, diagnostic self-evaluation.

References

1. Ferreira CT, Seidman E. Alergia alimentar: atualização prática do ponto de vista gastroenterológico. J. Pediatr. (Rio J.). 2007;83(1):7‑20.

2. Mahoney EJ, Veling MC, Mims JW. Food allergy in adults and children. Otolaryngol Clin North Am. 2011;44(3):815-33.

3. Schäfer T, Böhler E, Ruhdorfer S. Epidemiology of food allergy/ food intolerance in adults: associations with other manifestations of atopy. Allergy. 2002;57(2):178.

4. Solé D, Silva LR, Cocco RR, Ferreira CT, Sarni RO, Oliveira LC, et al. Consenso Brasileiro sobre Alergia Alimentar: 2018 - Parte 1 Etiopatogenia, clínica e diagnóstico. Documento conjunto elaborado pela Sociedade Brasileira de Pediatria e Associação Brasileira de Alergia e Imunologia. Arq Asma Alerg Imunol. 2018;2(1):7-38.

5. Sampson HA. Food allergy – Accurately identifying clinical reactivity. Allergy. 2005;60 Suppl.79:19-4.

6. Krogsboll LT, Jorgensen KJ, Gotzsche PC. General health checks in adults for reducing morbidity and mortality from disease. JAMA. 2013;309(23):2489-90.

7. Bock SA. Prospective appraisal of complaints of adverse reactions to foods in children during the first 3 years of life. Pediatrics. 1987;79:683-8.

8. Heinzerling L, Mari A, Bergmann KC, Bresciani M, Burbach G, Darsow U, et al. The skin prick test - European standards. Clin Transl Allergy. 2013;3(1):3.

9. Daher S, Galvão C, Abe A, Cocco R. Diagnóstico em doenças alérgicas Mediadas por IgE. Rev Bras Alerg Imunopatologia. 2009;1(32):3-8.

10. Prado EA, Soares FSP, Rizzo MC, Silva MGN, Rubini NP. O conhecimento de pediatras sobre alergia alimentar: estudo piloto. Rev Paul Pediatr. 2007;25(4):311-6.

11. Nekam KL. Nutritional triggers in asthma. Acta Microbiol Immunol Hung. 1998;45:113-7.

12. Nowak-Wegrzyn A, Bloom A, Sicherer SH, Shereffler WG, Noone S, Whanich N, et al. Tolerance to extensively heated milk in children with cow's milk allergy. J Allergy Clin Immunol. 2008;122(2):342-7.

13. Frongia O, Bellomo AR. Food allergies and intolerance in infants and children. Medico Bambino. 2005;24:533-8.

14. Soares A, Bruno J. Determinação da IgE específica para clara em crianças com alergia ao ovo. Rev Port Imunoalergologia. 2014;22(2):139-40.

15. Uberti F, Danzi R, Stockley C, Peñas E, Ballabio C, Lorenzo C, et al. Immuno-chemical investigation of allergenic residues in experimental and commercial-ly-available wines fined with egg white proteins. Food Chem. 2014;159:343-52.

16. Borges W. Alergia Alimentar - Uma abordagem prática. Departamento de Alergia e Imunologia Sociedade Brasileira de Pediatria. 2011;1‑25.

17. Gray CL, Goddard E, Karabus S, Kriel M, Lang AC, Manjra AI, et al. Epidemiology of IgE-mediated food allergy. South African Medical Journal 2015;105(1):68-9.

18. Altman M, Chiaramonte LT. Public perception of food allergy. Journal of Allergy and Clinical Immunology. 1996;97(6):1247‑51.

19. Elli L, Branchi F, Tomba C. Diagnosis of gluten related disorders: Celiac disease,wheat allergy and non-celiac gluten sensitivity. World Journal of Gastroenterology. 2015;21(23):7110-19.

20. El-Salhy M, Hatlebakk JG, Gilja OH, Hausken T. The relation between celiac disease,nonceliac gluten sensitivity and irritable bowel syndrome. Nutrition Journal. 2015;14:92.

21. Silva AT, Santa Marta C, Prates S, Almeida MM, Pinto JR. Hipersensibilidade ao trigo: formas de apresentação e proteínas alergênicas. Rev Port Imunoalergologia. 2005;13(2):133-40.

22. Ontiveros N. Prevalence of self-reported gluten-related disorders and adherence to a gluten-free diet in Salvadoran adult population. Int J Environ Res Public Health. 2018;15:786.

23. Robert SZ, Hugh A, Sampson SA, Bock AW, Burk K, Harden S, et al. Soy allergy in infants and children with IgE-associated cow’s milk allergy. J Pediatr. 1999;134(5):614-2.

24. Pasini G, Simonato B, Curioni A, Vincenzi S, Cristaudo A, Santucci B, et al. IgE-mediated allergy to corn: a 50 kDa protein, belonging to the Reduced Soluble Proteins, is a major allergen. Allergy. 2002;57(2):98-106.

25. Loveless MH. Allergy for corn and its derivatives: Experiments with a masked ingestion test for its diagnosis. J Allergy. 1950;21(6):500-9.

26. Fisher AA. Contact urticaria and anaphylactoid reaction due to corn starch surgical glove powder. Contact Dermatitis. 1987;16(4):224-5.

27. Verrill L, Bruns R, Luccioli S. Prevalence of self-reported food allergy in U.S. adults: 2001, 2006, and 2010. Allergy Asthma Proc. 2015;36(6):458-67.

28. Woods RK, Stoney SM, Raven J, Walters EH, Abramson M, Thien FCK. Reported adverse food reactions overestimate true food allergy in the community. Eur J Clin Nutr. 2002;56(1):31-6.

29. Carrapatoso I, Rodrigues F, Geraldes L, Faria E, Todo-Bom A, Loureiro C. Padrões clínicos e laboratoriais na hipersensibilidade ao camarão e reactividade cruzada com Dermatophagoides Pteronyssinus. Rev Port Imunoalergol. 2008;16 (5):449-66.

30. Raulf-Heimsoth M, Kespohl S, Crespo JF, Rodriguez J, Feliu A, Brüning T, et al. Natural rubber latex and chestnut allergy: crossreactivity or co-sensitization? Allergy. 2007;62(11):1277-81.


Submitted date:
09/22/2020

Accepted date:
09/29/2020

6a173deba95395309a2e36b6 aaai Articles
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Arq Asma Alerg Imunol

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