Arquivos de Asma, Alergia e Imunologia
https://aaai-asbai.org.br/article/doi/10.5935/2526-5393.20200043
Arquivos de Asma, Alergia e Imunologia
Special Article

Vacinas COVID-19 e reações imunoalérgicas

COVID-19 vaccines and immunoallergic reactions

Fátima Rodrigues Fernandes; Ana Karolina B. Berselli Marinho; Mônica de Araújo Álvares da Silva; Claudia Leiko Yonekura Anagusko; Adriana Azoubel Antunes; Cláudia França Cavalcante Valente; Irma C. Douglas Barreto; Lorena de Castro Diniz; Alexandra S. Watanabe; Renata Rodrigues Cocco; Marcelo Vívolo Aun; Pedro Giavina-Bianchi; Ekaterini Simões Goudouris; Dirceu Solé; Flávio Sano

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Resumo

A avaliação dos riscos e benefícios deve ser realizada para qualquer intervenção preventiva, diagnóstica ou terapêutica em Medicina. As vacinas, assim como qualquer imunobiológico, são consagradas pelas inúmeras vantagens inerentes à proteção da saúde, apesar dos potenciais riscos de eventos adversos que, na imensa maioria das vezes, são raros, leves e controláveis. O desenvolvimento de vacinas contra o novo SARS-CoV-2 representa um dos principais anseios da população mundial e representa extraordinário avanço da Ciência. Pacientes com histórico de alergias graves a algum componente das vacinas ou a uma dose prévia de alguma delas, devem ser avaliados com cautela pelo especialista para decidir se esta deverá ser contraindicada, aplicada com supervisão médica, ou se estará indicado protocolo de dessensibilização.

Palavras-chave

Vacina COVID-19, reações imunoalérgicas, anafilaxia.

Abstract

The assessment of risks and benefits must be carried out for any preventive, diagnostic, or therapeutic intervention in medicine. Vaccines, like any biologic, are recognized for the innumerable advantages in public health, despite the potential risks of adverse events that, in the vast majority of cases, are rare, mild, and controllable. The development of vaccines against the new SARSCoV-2 represents one of the main wishes of the world population as well as an extraordinary advance in science. Patients with a history of severe allergies to any component of the vaccines or reaction to a previous dose of any of them should be carefully evaluated by the specialist to decide whether vaccination should be contraindicated or administered with medical supervision, or if a desensitization protocol will be indicated.

Keywords

COVID-19 vaccine, immunoallergic reactions, anaphylaxis.

References

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Submitted date:
12/19/2020

Accepted date:
12/20/2020

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