Arquivos de Asma, Alergia e Imunologia
https://aaai-asbai.org.br/article/doi/10.5935/2526-5393.20190033
Arquivos de Asma, Alergia e Imunologia
Comunicação Clínica e Experimental

Mepolizumabe na doença respiratória exacerbada por aspirina - DREA

Mepolizumab in aspirin-exacerbated respiratory disease - AERD

Mariele Morandin Lopes; Claudia Leiko Yonekura Anagusko; Fábio Fernandes Morato Castro

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Resumo

Relato de caso que ilustra a eficácia e a segurança do uso do mepolizumabe na doença respiratória exacerbada por aspirina (DREA). A utilização de anticorpo monoclonal no tratamento desta doença respiratória de difícil tratamento tem possibilitado o controle da inflamação crônica e o maior conhecimento sobre a fisiopatogenia da doença.

Palavras-chave

Anticorpos monoclonais, asma induzida por aspirina, interleucina-5.

Abstract

This case report shows the efficacy and safety of mepolizumab in aspirin-exacerbated respiratory disease (AERD). The use of monoclonal antibodies in the treatment of this severe disease has provided improved control of chronic inflammation and greater understanding about the pathophysiology of the disease.

Keywords

Monoclonal antibodies, aspirin-induced asthma, interleukin-5.

Referências

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Submetido em:
29/05/2019

Aceito em:
11/06/2019

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