Imunodeficiência comum variável: dificuldades no diagnóstico
Common variable immunodeficiency: diagnostic constraints
Karin Milleni Araujo; Licio Augusto Velloso; Eli Mansour
Resumo
A imunodeficiência comum variável (IDCV) é a imunodeficiência primária sintomática mais comum, e representa um conjunto heterogêneo de distúrbios que resultam principalmente da deficiência de anticorpos, levando a infecções recorrentes. A variabilidade na expressão clínica e o desconhecimento da doença contribuem para o retardo no diagnóstico, aumentando a morbidade e a mortalidade. Neste artigo apresentamos o caso clínico de um jovem diagnosticado com IDCV, ressaltando as dificuldades para se estabelecer o diagnóstico frente aos múltiplos achados clínicos e laboratoriais durante o processo de investigação. Tal fato levou a hospitalização prolongada, com grande número de complicações graves e elevado custo.
Palavras-chave
Abstract
Common variable immunodeficiency (CVID) is the most common symptomatic primary immunodeficiency. It accounts for a heterogeneous group of disorders resulting mostly in antibody deficiency and thus leading to recurrent infections. Great variability of clinical expression and poor knowledge of the disease contribute to delayed diagnosis, increasing morbidity and mortality. In this paper, we describe the clinical case of a young adult male diagnosed with CVID, highlighting the difficulties faced while establishing the diagnosis in view of the multiple clinical and laboratory findings observed during the investigation process, which resulted in prolonged hospitalization, with severe complications and elevated costs.
Keywords
References
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Submitted date:
10/03/2015
Accepted date:
07/05/2016
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