1. Pawankar R. Allergic diseases and asthma: a global public health concern and a call to action. World Allergy Organ J. 2014;7(1):12.

2. Platts-Mills TAE. The allergy epidemics: 1870-2010. J Allergy Clin Immunol. 2015;136:3-13.

3. Lack G, Plaut M, Sayre PH. Peanut consumption in infants at risk for peanut allergy. N Engl J Med. 2015;372(22):2165-6.

4. Chang A, Robison RG, Cai M, Singh AM. Natural history of foodtriggered atopic dermatitis and development of immediate reactions in children. J Allergy Clin Immunol Pract. 2016;4(2):229-36.

5. Aho VT, Pereira PA, Haahtela T, Pawankar R, Auvinen P, Koskinen K. The microbiome of the human lower airways: a next generation sequencing perspective. World Allergy Organ J. 2015;8(1):23.

6. Lynch SV and Boushey AH. The microbiome and development of allergic disease. Curr Opin Allergy Clin Immunol. 2016;16:165‑71.

7. Strachan DP. Hay fever, hygiene, and household size. BMJ. 1989;299:1259-60.

8. Smits HH, Hiemstra PS, Prazeres da Costa C, Ege M, Edwards M, Garn H, et al. Microbes and asthma: opportunities for intervention. J Allergy Clin Immunol. 2016;137(3):690-7.

9. von Mutius E. The microbial environment and its influence on asthma prevention in early life. J Allergy Clin Immunol. 2016;137:680-9.

10. Arrieta MC, Stiemsma LT, Dimitriu PA, Thorson L, Russell S, Yurist-Doutsch S, et al. Early infancy microbial and metabolic alterations affect risk of childhood asthma. Sci Transl Med. 2015;7(307):307ra152.

11. Holt PG. The mechanism or mechanisms driving atopic asthma initiation: The infant respiratory microbiome moves to center stage. J Allergy Clin Immunol. 2015;136:15-22.

12. von Mutius E, Vercelli D. Farm living: effects on childhood asthma and allergy. Nat Rev Immunol. 2010;10:861-8.

13. Ege MJ, Mayer M, Normand AC, Genuneit J, Cookson WO, BraunFahrlander C, et al. Exposure to environmental microorganisms and childhood asthma. N Engl J Med. 2011;364:701-9.

14. Fall T, Lundholm C, Örtqvist AK, Fall K, Fang F, Hedhammar Å, et al. Early exposure to dogs and farm animals and the risk of childhood asthma. JAMA Pediatr. 2015;169(11):e153219.

15. Fujimura KE, Johnson CC, Ownby DR, Cox MJ, Brodie EL, Havstad SL, et al. Man's best friend? The effect of pet ownership on house dust microbial communities. J Allergy Clin Immunol. 2010;126(2):410-2.

16. Fujimura KE, Demoor T, Rauch M, Faruqi AA, Jang S, Johnson CC, et al. House dust exposure mediates gut microbiome Lactobacillus enrichment and airway immune defense agains allergens and virus infection. Proc Natl Acad Sci USA. 2014;111(2):805-10.

17. Stokholm J, Thorsen J, Chawes BL, Schjørring S, Krogfelt KA, Bønnelykke K, et al. Cesarean section changes neonatal gut colonization. J Allergy Clin Immunol. 2016 Apr 1. pii: S0091- 6749(16)00296-7. doi:10.1016/j.jaci.2016.01.028.

18. Reis AP. Epigenética da asma: revisão. Braz J Allergy Immunol. 2015;3(1):13-8.

19. Beasley R, Semprini A, Mitchell EA. Risk factors for asthma: is prevention possible? Lancet. 2015; 386:1075-85.

20. Cuello-Garcia CA, Brożek JL, Fiocchi A, Pawankar R, Yepes-Nuñez JJ, Terracciano L, et al. Probiotics for the prevention of allergy: A systematic review and meta-analysis of randomized controlled trials. J Allergy Clin Immunol. 2015;136(4):952-61.

21. Duarte IK, Vieira RP, Graudenz GS. Análise das tendências das internações hospitalares por asma no Brasil de 1998 a 2010. Braz J Allergy Immunol. 2015;3(1):19-24.

22. Levy ML. The national review of asthma deaths: what did we learn and what needs to change? Breathe (Sheff). 2015;11(1):14-24.

23. Levy ML, Winter R. Asthma deaths: what now? Thorax. 2015;70(3):209‑10.

24. Cope EK, Lynch SV. Novel microbiome-based therapeutics for chronic rhinosinusitis. Curr Allergy Asthma Rep. 2015 Mar;15(3):504. doi: 10.1007/s11882-014-0504-y.