Recomendações para o diagnóstico de alergia ao látex
Recommendations for the diagnosis of latex allergy
Adriano Bueno de Sá; Laila Sabino Garro; Fátima Rodrigues Fernandes; Maria Cândida V. Rizzo; Leda das Neves A. Sandrin; Luis Felipe Ensina; Dirceu Solé; Grupo de Interesse em Alergia a Medicamentos (GIAM)
Resumo
Objetivo: Fornecer uma atualização das condutas atuais baseadas em evidências, no que diz respeito à abordagem da alergia ao látex, de forma prática e objetiva.
Fontes de dados: Foram utilizados os bancos de dados: Pubmed e Lilacs; artigos de revisão, manuais de conduta prática e atualizações no tema.
Síntese de dados: Este artigo enfoca os parâmetros práticos da conduta em pacientes com história de alergia ao látex.
Conclusões: A alergia ao látex constitui um grande desafio na prática diária do médico alergista, especialmente no que se refere ao diagnóstico diferencial das reações de hipersensibilidade aos medicamentos. Desta forma, é importante abordar este tópico de forma clara e prática, a fim de auxiliar o médico especialista a conduzir de forma correta a investigação dos casos suspeitos.
Palavras-chave
Abstract
Objective: This document was developed as an updated practice parameter to improve the care of patients by providing the practicing physician with an evidence-based approach in the management of latex allergy.
Sources: Medline and Lilacs databases; review papers, practice parameters and updates in beta lactam allergy management.
Data synthesis: This is a practice parameter review on latex allergy management.
Conclusions: Latex allergy results in major health problems for allergists, especially regarding the differential diagnosis in drug hypersensitivity. Knowledge of the latex allergic patient management is very important in the investigation of suspected subjects.
Keywords
Referências
1. Bernardini R, Novembre E, Ingargiola A, Veltroni M, Mugnaini L, Cianferoni A, et al. Prevalence and risk factors of latex sensitization in an unselected pediatric population. J Allergy Clin Immunol 1998;101(5):621-5.
2. Konz KR, Chia JK, Kurup VP, Resnick A, Kelly KJ, Fink JN. Comparison of latex hypersensitivity among patients with neurologic defects. J Allergy Clin Immunol 1995;95(5 Pt 1):950-4.
3. Charous BL, Blanco C, Tarlo S, Hamilton RG, Baur X, Beezhold D, et al. Natural rubber latex allergy after 12 years: recommendations and perspectives. J Allergy Clin Immunol 2002;109(1):31-4.
4. ALLERGEN NOMENCLATURE. IUIS Allergen Nomenclature SubCommittee. Disponível em: http://www.allergen.org/search.ph p?allergensource=latex&searchsource=Search. Acessado em 05 de setembro de 2012.
5. Bernstein DI, Biagini RE, Karnani R, Hamilton R, Murphy K, Bernstein C, et al. In vivo sensitization to purified Hevea brasiliensis proteins in health care workers sensitized to natural rubber latex. J Allergy Clin Immunol 2003;111(3):610-6.
6. Wagner B, Buck D, Hafner C, Sowka S, Niggemann B, Scheiner O, et al. Hev b 7 is a Hevea brasiliensis protein associated with latex allergy in children with spina bifida. J Allergy Clin Immunol 2001;108(4):621-7.
7. Bousquet J, Flahault A, Vandenplas O, Ameille J, Duron JJ, Pecquet C, et al. Natural rubber latex allergy among health care workers: a systematic review of the evidence. J Allergy Clin Immunol 2006;118(2):447-54.
8. Weissman DN, Lewis DM. Allergic and latex-specific sensitization: route, frequency, and amount of exposure that are required to initiate IgE production. J Allergy Clin Immunol 2002;110(Suppl 2):S57-63.
9. Yunginger J. Natural rubber latex allergy. 7 ed. Adkinson Jr NF BB, Busse WW, Holgate ST, Lemanske Jr RF, Simons FER, editor. Philadelphia, Pensilvania: Mosby; 2009.
10. Faria E, Sousa N, Geraldes L, Santos A, Chieira C. Anafilaxia perioperatória em Coimbra: Experiência da consulta de alergia a fármacos. Rev Port Imunoalergol 2008;16(1):73-92.
11. Taylor JS, Erkek E. Latex allergy: diagnosis and management. Dermatol Ther 2004;17(4):289-301.
12. Wakelin SH, White IR. Natural rubber latex allergy. Clin Exp Dermatol 1999;24(4):245-8.
13. Binkley MH, Schroyer T, Catalfano J. Latex Allergies: A Review of recognition, evaluation, management, prevention, education, and alternative product use. J Athl Train 2003;38(2):133-40.
14. Lopes I. Manifestações clínicas. Rev Port Imunoalergol 2005;13(1):19-22.
15. Sussman GL, Tarlo S, Dolovich J. The spectrum of IgE-mediated responses to latex. JAMA 1991;265(21):2844-7.
16. Sanchez-Monge R, Blanco C, Perales AD, Collada C, Carrillo T, Aragoncillo C, et al. Class I chitinases, the panallergens responsible for the latex-fruit syndrome, are induced by ethylene treatment and inactivated by heating. J Allergy Clin Immunol 2000;106(1 Pt 1):190-5.
17. Pi re s G . Ale rgia C ru zada . Rev Po r t Imunoale rgol 2005;13(1):23-6.
18. Almeida CA, Perini PG, Curi SV, Fernandes FR, Andrade MEB, Aun WT, et al. Alergia ao Látex tipo I e alergia alimentar. Rev bras alerg imunopatol 2010;33(4):123-6.
19. Bernardini R, Pucci N, Azzari C, Novembre E, De Martino M, Milani M. Sensitivity and specificity of different skin prick tests with latex extracts in pediatric patients with suspected natural rubber latex allergy – A cohort study. Pediatr Allergy Immunol 2008;19:315-8.
20. Nettis E, Dambra P, Soccio AL, Ferrannini A, Tursi A. Latex hypersensitivity: relationship with positive prick test and patch test responses among hairdressers. Allergy 2003;58(1):57-61.
21. Nicolaou N, Johnston GA. Anaphylaxis following prick testing with natural rubber latex. Contact Dermatitis 2002;47(4):251-2.
22. Yunginger JW, Jones RT, Fransway AF, Kelso JM, Warner MA, Hunt LW. Extractable latex allergens and proteins in disposable medical gloves and other rubber products. J Allergy Clin Immunol 1994;93(5):836-42.
23. Hamilton RG, Peterson EL, Ownby DR. Clinical and laboratorybased methods in the diagnosis of natural rubber latex allergy. J Allergy Clin Immunol 2002;110(2):47-56.
24. Hamilton RG, Adkinson NF Jr. Natural rubber latex diagnostic skin testing reagents: safety and efficacy of nonammoniated latex, ammoniated latex, and latex rubber glove extracts. J Allergy Clin Immunol 1996;98:872-83.
25. Hamilton RG. Diagnosis of natural rubber latex allergy. Methods 2002;27:22-31.
26. Carvalho F. Diagnóstico imunoalergológico. Rev Port Imunoalergol 2005;13(1):27-30.
27. Liccardi G, D’Amato G, Canonica GW, Salzillo A, Piccolo A, Passalacqua G. Systemic reactions from skin testing: literature review. J Investig Allergol Clin Immunol 2006;16(2):75-8.
28. Johansson SGO. ImmunoCAP® specific IgE test: an objective tool for research and routine allergy diagnosis. Expert Rev Mol Diagn 2004;4(3):273-9.
29. Biagini RE, MacKenzie BA, Sammons DL, Smith JP, Krieg EF, Robertson AS, et al. Latex specific IgE: performance characteristics of the IMMULITE 2000 - Allergy assay compared with skin testing. Ann Allergy Asthma Immunol 2006;97:196-202.
30. Shreffler WG. Microarrayed recombinant allergens for diagnostic testing. J Allergy Clin Immunol 2011;127(4):843-9.
31. Nucera E, Schiavino D, Pollastrini E, Rendeli C, Pietrini D, Tabacco F, et al. Sublingual desensitization in children with congenital malformations and latex allergy. Pediatr Allergy Immunol 2006;17:606-12.
32. Jaeger D, Kleinhans D, Czuppon AB, Baur S. Latex-specific proteins causing immediate-type cutaneous, nasal, bronchial, and systemic reactions. J Allergy Clin Immunol 1992;89:759-68.
33. Palczynski C, Walusiak J, Ruta U, Gorski P. Nasal provocation test in the diagnosis of natural rubber latex allergy. Allergy 2000:55:34-41.
34. Niggemann B, Buck D, Michael T, Wahn U. Latex provocation tests in patients with spina bifida: Who is at risk of becoming symptomatic? J Allergy Clin Immunol 1998;102:665-70.
35. Kelly KJ, Kurup VP, Reijula KE, Fink JN. The diagnosis of natural rubber latex allergy. J Allergy Clin Immunol 1994;93:813-6.
36. Ahmed DDF, Sobczak SC, Yunginger JW. Occupational allergies caused by latex. Immunol Allergy Clin N Am 2003;23:205-19.
Submetido em:
14/09/2012
Aceito em:
25/10/2012
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