Alergia ao amendoim: revisão
Peanut allergy: review
Lucila Camargo Lopes de Oliveira; Dirceu Solé
Resumo
Objetivo: Revisar a literatura para um melhor manejo do paciente com alergia a amendoim.
Fonte de dados: Artigos originais indexados no banco de dados do MEDLINE no período de janeiro de 1990 a dezembro de 2011 nos idiomas português e inglês, além de sites específicos na Internet. Palavras-chave: alergia, atopia, amendoim, Arachis hypogaea.
Síntese dos dados: O amendoim é um dos principais alimentos relacionados a manifestações alérgicas. Com início geralmente na infância, a alergia ao amendoim comumente associa-se a outras manifestações atópicas e à anafilaxia. O padrão ouro para diagnóstico permanece o teste de provocação oral, embora outros parâmetros imunológicos se mostrem promissores, como o diagnóstico resolvido por componentes (CRD-Component resolved diagnosis). Por determinar importante prejuízo na qualidade de vida destes pacientes e ser sua duração prolongada, na maioria dos casos, tem sido objeto de estudos de novas opções terapêuticas.
Conclusões: Embora certamente o amendoim não se encontre entre os principais alimentos causadores de manifestações alérgicas observadas na prática clínica em nosso país, casos existem e é preciso saber o melhor manejo destes pacientes.
Palavras-chave
Abstract
Objective: Review of the literature for a better handling of the patient with peanut allergy.
Sources: English and Portuguese written original articles indexed on the MEDLINE databases from the period of January 1990 to December 2011 and also specific sites on the Internet. Key words: allergy, atopy, peanut, Arachis hypogaea.
Data synthesis: Peanut is one of the main food allergy related sources. Beginning normally in childhood, peanut allergy is often associated with other atopic diseases and anaphylaxis. Oral food challenge remains the gold standard method for diagnosis although other immunological parameters, like component resolved diagnosis, seem promising. Accounting for an important impairment of the quality of life and long lasting symptoms, it is the objective of studies on new therapeutic options.
Conclusions: Although certainly peanut is not one of the main food allergens in Brazil, there are cases and it is necessary knowing how to handle those.
Keywords
Referências
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Submetido em:
20/01/2012
Aceito em:
22/02/2012
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